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M. tuberculosis H37Rv Rv2446c (-)

annotation: PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN
coordinates: 2745767 - 2746138
length: 123

TDRSREPADPWKGFSAVMAATLILEAIVVLLAIPVVDAVGGGLRPASLGYLVGLAVLLILLTGLQRRPWA
IWVNLGAQPVLVAGFAVYPGVGFIGVLFAALWVLIAYLRAEVRRRRDYRVSQ*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2446c--100% (123)PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2473c-5e-66100.00% (123) integral membrane protein
M. gilvum PYR-GCKMflv_2632-8e-3965.49% (113) hypothetical protein Mflv_2632
M. leprae Br4923MLBr_01470-3e-3666.67% (108) hypothetical protein MLBr_01470
M. abscessus ATCC 19977MAB_1605-1e-3461.82% (110) hypothetical protein MAB_1605
M. marinum MMMAR_3770-4e-4468.80% (125) hypothetical protein MMAR_3770
M. avium 104MAV_1726-2e-4879.82% (114) hypothetical protein MAV_1726
M. smegmatis MC2 155MSMEG_4628-5e-3460.87% (115) hypothetical protein MSMEG_4628
M. thermoresistible (build 8)TH_3032-8e-3150.00% (116) PUTATIVE conserved hypothetical protein
M. ulcerans Agy99MUL_3717-3e-4367.20% (125) hypothetical protein MUL_3717
M. vanbaalenii PYR-1Mvan_3949-6e-4169.09% (110) hypothetical protein Mvan_3949

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2632|M.gilvum_PYR-GCK          ---------------MS-TPPPDPWKSFRGVMAGTLILEAIVVLLALPVV
Mvan_3949|M.vanbaalenii_PYR-1       ---------------MNGQPPPDPWKSFRGVMAGTLILEAIVVLLALPVV
MAB_1605|M.abscessus_ATCC_1997      MSDPEDGIEPRADQNVAGAAPPDPWRSFRGVMAGTLILETIVVLLAIPVV
Rv2446c|M.tuberculosis_H37Rv        MTD----------RSREPA---DPWKGFSAVMAATLILEAIVVLLAIPVV
Mb2473c|M.bovis_AF2122/97           MTD----------RSREPA---DPWKGFSAVMAATLILEAIVVLLAIPVV
MAV_1726|M.avium_104                MTRPDPPEGP---QQRGAA---DPWRSFGAVMAATLILEAIVVLLAIPVV
MMAR_3770|M.marinum_M               MTG-QPQEPA---NHGDPAPQSDPWKSFGSVMAATLILEAIVVLLAIPVV
MUL_3717|M.ulcerans_Agy99           MTG-QPQEPA---NHGDPAPQSDPWKSFGSVMTATLTLEAIVVLLAIPVV
MLBr_01470|M.leprae_Br4923          MTDSPGEHGP---QKPLPS--ADPWKSFAGVMAAILFLEAIVVLLALPVL
MSMEG_4628|M.smegmatis_MC2_155      MSENQA-------PDNEPAPAKDPWKSFRGVMAACLILEAIVVLLALPVV
TH_3032|M.thermoresistible__bu      MSE-------------QPARRPDPWRSFRGVMAGTLLLEAIVMVLALPVV
                                                          ***:.* .**:. * **:**::**:**:

Mflv_2632|M.gilvum_PYR-GCK          GAVGPGLTPFSTAYVIGFAVLLVVMAGVQGRGWAIWANVGVQLLLVAGWF
Mvan_3949|M.vanbaalenii_PYR-1       GAVGPGLTAGSTGYVIGVAVLLVLMSGVQGRPWAIWANLGVQLLLVAGWF
MAB_1605|M.abscessus_ATCC_1997      KMVGGGLSPLSLSYLIGVVVALVLLCGMQGRPWALQANLALQLVLVAGFL
Rv2446c|M.tuberculosis_H37Rv        DAVGGGLRPASLGYLVGLAVLLILLTGLQRRPWAIWVNLGAQPVLVAGFA
Mb2473c|M.bovis_AF2122/97           DAVGGGLRPASLGYLVGLAVLLILLTGLQRRPWAIWVNLGAQPVLVAGFA
MAV_1726|M.avium_104                GAVGGGLTRVSLGYLIGLAVLLVLLAGVQRRPWAIWVNLGAQAILLAGFA
MMAR_3770|M.marinum_M               GAVGGGLTPASLGYLIGLAVTLVLLAGVQRRPWAIWANLGIQLVPIAGVF
MUL_3717|M.ulcerans_Agy99           GAVGGGLTPASLGYLIGLAVTLVLLAGVQRRPWAIWANLGIQLVPIAGVF
MLBr_01470|M.leprae_Br4923          GASGG-LTLSALSFLIGLAGLLIVLVGLQRKAWAIWVNLGVQVVVLVGCA
MSMEG_4628|M.smegmatis_MC2_155      AVG--GLSAAAGGYLIGLAVVLILMCGVQGRPWALWANLGMQVPVIAGAV
TH_3032|M.thermoresistible__bu      VQAQNGFTATGGGFVVALTLALVALAGVQGRPWALWVNIAMQFVVIAGVL
                                          :   . .:::...  *: : *:* : **: .*:. *   :.*  

Mflv_2632|M.gilvum_PYR-GCK          LYPGVGFIGLLFFVVWLLIAYLRAEVLRRQKRGLLPGQSG--GDH
Mvan_3949|M.vanbaalenii_PYR-1       IYPGVGFIGLLFVVVWLLIAYLRAEVLRRQKRGLLPGQQP--TDD
MAB_1605|M.abscessus_ATCC_1997      VNAAVGFVGLLFLGVWLLIWYMRNQVRDRQSRGELPGQQGSATDQ
Rv2446c|M.tuberculosis_H37Rv        VYPGVGFIGVLFAALWVLIAYLRAEVRRR--RDYRVSQ-------
Mb2473c|M.bovis_AF2122/97           VYPGVGFIGVLFAALWVLIAYLRAEVRRR--RDYRVSQ-------
MAV_1726|M.avium_104                VYPGVGFIGVLFTGLWALIAYFRAEVRRR--QG------------
MMAR_3770|M.marinum_M               VYPAVGFLGVVFGAVWAMMAYFRAEVRRRERQGPPPSR-------
MUL_3717|M.ulcerans_Agy99           VYPAVGFLGVVFGAVWAMMAYFRAEVRRRERQGPPPSR-------
MLBr_01470|M.leprae_Br4923          VYPVLGFVGVLFAGLWALIVYFRAEVSRR----------------
MSMEG_4628|M.smegmatis_MC2_155      FHGGIGFIGVVFLVVWLLIVYLRHEVKRRQERGLLPGQQRPAE--
TH_3032|M.thermoresistible__bu      VHGAIGFVGVLFLAVWLFIAYLRAEVKRREARGELPGQQAGEE--
                                    .   :**:*::*  :* :: *:* :*  *